ELISA for active form of vitamin B12
Current front-line biochemical tests for assessment of Vitamin B12 status suffer from several important limitations including both false positives and false negatives, a wide indeterminate range and measurement of both active and inactive B12. Hematological test results can also be non-specific or misleading. The Active-B12 assay from Axis-Shield provides an innovative and highly accurate method for assessing Vitamin B12 status. The assay measures holotranscobalamin, the bio-active form of the vitamin. Holotranscobalamin represents only 10-30% of circulating B12 but is the only form taken up and utilized by the cells of the body – the Active-B12 assay therefore gives a more accurate assessment of the body’s B12 status. The CE-marked Active-B12 assay is a standard 96-well ELISA with break-apart strips and is supplied with all required reagents, calibrators and controls. The kit is compatible with liquid- handling automated instruments for higher throughput.