First clinical proof of principle for T-Track TB for detection of active tuberculosis

Effective diagnosis and treatment of tuberculosis (TB) is notoriously difficult and the incidence of drug-resistant strains is increasing. However, using T-cell based diagnostic test systems,  Lophius Biosciences has achieved its first successfully concluded clinical Proof of Principle study with respect to detection of active TB using its novel T-Track TB test, which is based on the company’s proprietary Reverse T Cell Technology (RT Technology). The clinical Proof of Principle was concluded in India with a cohort of 44 patients. Results demonstrated that the new TB test was able to detect active TB in in 10 of 12 non-treated patients. Besides its high sensitivity and specificity the test also demonstrated a remarkably short turnaround time of 2 days, which compares favourably to currently used detection methods. These results suggest that the T-Track TB test could represent an innovative and fast detection approach for this area of strong medical need.

http://tinyurl.com/cm6r8e4