H. pylori rapid test

ASSURE

H. pylori rapid test

Helicobacter pylori (H. pylori) is a cork-screw-spiral-like gram-negative bacterium that has adapted to grow in the human stomach. The prevalence of H. pylori infection worldwide is approximately 66%,...

Supplied by MP Biomedicals- Diagnostics


Helicobacter pylori (H. pylori) is a cork-screw-spiral-like gram-negative bacterium that has adapted to grow in the human stomach. The prevalence of H. pylori infection worldwide is approximately 66%, and in developing countries, it is as high as 80% – 90%. The testing and treatment of H. pylori is very important as it has been estimated that up to 20% of people infected with H. pylori will develop ulcers which may lead to specific cancers. MP Diagnostics ASSURE H. pylori Rapid Test and Helico Blot 2.1 Western Blot incorporate a unique marker, CIM, which is used to detect the current infection of H. pylori bacteria. CIM stands for Current Infection Marker which is actually a H. pylori-specific protein. The nucleotide sequence of the CIM antigen is homologous to a conserved secreted protein. This protein has been found to be highly immunogenic for detection of H. pylori infected patients with high Positive Predictive Value of >90%. It has been coined as Current Infection Marker because IgG antibodies for CIM have been found in patients with active H. pylori infection. These patients are confirmed to have active H. pylori infection by two or more active infection diagnostic tests such as rapid urease test, culture, histology, and Urea Breath Test. With CIM-based products, no additional tests are needed for detecting current H. pylori infection.


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