HSV1, HSV2 and VZV viral DNA test
The EurobioPlex HSV-1, HSV-2 and VZV kit, which obtained the CE mark, is a real-time amplification test of viral DNA of each of these viruses, with specific detection, as well as a DNA extraction and PCR inhibition control. This ready to use test is performed from extracted DNA, or directly on cerebrospinal fluid (CSF) without extraction using a reaction in a single well/tube. The test is indicated to detect and specifically differentiate the DNA of these viruses, and thus to diagnose the occurrence of infection by these viruses in humans, or to supplement a proven or undetermined diagnosis. Time from sample to result is short: less than 35 min. on standard PCR instruments such as CFX96 (Bio-Rad) or LC480 (Roche), and 1h on the 8-well, single-patient testing TCOR8-IVD instrument (Tetracore), networkable (WiFi/Ethernet) for remote access and data download. The Eurobio-Plex HSV1-HSV2-VZV has been validated on the following specimens: plasma, blood, amniotic fluid, various biological samples with cellular components (skin, eye, pharynx, tongue, colon, penis, foreskin, anogenital and vaginal areas, naso-pharyngeal aspirations), and directly on CSF.
Human herpesviruses are enveloped linear double-stranded DNA viruses belonging to the family Herpesviridae. Their DNA replication and transcription of their genes occur in the nucleus of infected cells. They are subdivided into three groups: alpha-, beta – and gamma herpesviridae. Primary infection with herpes virus is common and most infections occur during childhood. Many Infections with varying degrees can occur at any age, resulting in various diseases: skin lesion (herpes eczema), encephalitis, neonatal herpes and disseminated herpes. A special case is that of VZV, responsible for chickenpox, characterized by moderate fever and a vesicular eruption. Generally benign for children, there is a risk of severe complications when it is contracted by adults, immunosuppressed people and pregnant women. The reactivation of the virus in the body leads to the appearance of zona. Fast direct detection from CSF with EurobioPlex HSV1-HSV2-VZV constitutes a powerful tool for the diagnosis of meningitis.
Supplier: Eurobio Scientific
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