Human MxA Protein ELISA

Human MxA Protein ELISA

Human MxA Protein ELISA

Designed for the measurement of MxA protein in human whole blood, an innovative ELISA based on the use of patented monoclonal antibodies and a special buffer to extract the cytoplasmic MxA protein is suitable...

Supplied by BioVendor Research and Diagnostic Products


Designed for the measurement of MxA protein in human whole blood, an innovative ELISA based on the use of patented monoclonal antibodies and a special buffer to extract the cytoplasmic MxA protein is suitable for the monitoring of IFN-β therapy in multiple sclerosis patients and for viral infection recognition. Human Myxovirus protein A is induced exclusively by IFN-α and IFN-β. Since direct measurement of the IFN levels in plasma is difficult, MxA may be useful as a marker distinguishing viral disease from bacterial infection or from acute graft-versus-host disease after allogenic stem cell transplantation. Neutralizing antibodies may develop during the IFN-β therapy of multiple sclerosis and lead to loss of drug bioactivity. The IFN-β-inducible MxA protein is an ideal marker of IFN-β bioavailability, capable of discriminating between biologically responsive and non-responsive patients. The BioVendor assay meets all the requirements for routine clinical use in manual mode as well as on open ELISA robotic systems.


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