S100A11 ELISA
S100A11 (S100C, Calgizzarin) is a Ca2+-binding protein of the S100 family that has been implicated in the regulation of cytoskeletal function through its Ca2+-dependent interaction with annexin I. S100A11 has been found in many different human tissues, both normal and cancerous. S100A11 appears to play distinct roles depending on the tumour involved. In bladder carcinoma or renal carcinoma, its expression is related to tumour suppression, however in prostate cancer, breast and pancreatic cancer, S100A11 is thought to be a tumour promoter. S100A11 may be a potential biomarker of infective endocarditis. Recently, increased S100A11 concentrations have also been found in patients with pulmonary diseases – COPD, idiopathic pulmonary fibrosis (IPF) and sarcoidosis. The assay has been validated to measure S100A11 in serum, bronchoalveolar lavage fluid and amniotic fluid. The 96 well-microtitre plate format ensures the applicability on standard ELISA equipment or robotic systems.
Supplier: BioVendor Research and Diagnostic Products
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