C202 Biosystems crop 01

Unsaturated iron binding capacity reagent

A new reagent for measurement of unsaturated iron binding capacity (UIBC) in serum and plasma based on the direct method doesn’t require any manual precipitation process. Serum Iron is transported from one organ to another as Fe3+ by apotransferrin, a plasma iron transport protein. The apotransferrin-Fe3+ complex is called transferrin. Normally, only about one third of the iron binding sites of transferrin are occupied by iron. The additional amount of iron that can be bound is the Unsaturated Iron Binding Capacity (UIBC). The sum of iron concentration and UIBC represents the Total Iron Binding Capacity (TIBC). A decrease in Iron Binding Capacity may be due to hemochromatosis, acute iron poisoning, active cirrhosis or acute hepatitis. Iron binding capacity is usually increased in anemia by iron deficiency. BioSystems introduces this method (Ferrozine – differential bireagent) in its portfolio for both manual and automated systems.


Supplier: BioSystems
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