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301

New triterpene discovery overturns current knowledge of highly useful compound, opening up new world for drug discovery

A remarkable discovery and collaborative effort have revealed a new type of triterpenes, a group of organic compounds which are an important source of many medicines. Until now, all triterpenes were believed to be derived from squalene, itself a type of triterpene. However, for the first time, researchers witnessed biosynthesis, the formation of complex compounds […]

302

CYTENA and ExcellGene to develop automated workflows for biotherapeutics cell line development

CYTENA, a BICO group company and a leading provider of high-precision instruments for handling biological cells, has entered a collaboration agreement with ExcellGene SA, a leading biologics Contract Development & Manufacturing Organization (CDMO) that manufactures recombinant proteins. Together, the companies will streamline cell line development workflows for highly-efficient monoclonal antibody (mAb) and complex therapeutic protein […]

304

KNAUER wins German Innovation Award 2022

KNAUER Wissenschaftliche Geräte, a developer of laboratory instruments and known for their liquid chromatography systems and components, was honoured with the German Innovation Award 2022 in Munich in April for their design and manufacture of large-scale plants, at its own risk, for the ncapsulation of mRNA for COVID-19 vaccines. Equipment for the production of millions of mRNA vaccine doses had […]

305

Greiner Bio-One appoints new head of business for Preanalytics

Dr Stefan Gebauer has taken over management of the “Preanalytics” product division at Greiner Bio-One in Kremsmünster, Austria. He has many years of professional and management experience in the healthcare industry, focussing primarily on medical products in the IVD sector. Before joining Greiner Bio-One, he successfully managed the “Therapy Management” product line at Bosch Healthcare […]

309

Gene editing DNA deletion sizes reduced with new fusion method

Wake Forest Institute for Regenerative Medicine (WFIRM) scientists working on CRISPR/Cas9-mediated gene editing technology have developed a method to increase efficiency of editing while minimizing DNA deletion sizes, a key step toward developing gene editing therapies to treat genetic diseases.

310

Researchers discover new molecular mechanism in promoting melanoma angiogenesis and metastasis

A research team at LKS Faculty of Medicine, The University of Hong Kong (HKUMed) has discovered a new molecular pathway to govern melanoma angiogenesis and metastasis. The findings provide new insights into how melanoma undergoes metastasis and progression through secretion of pro-angiogenic factor to induce angiogenesis that paves the way for new therapeutic opportunities. The […]