Active vitamin B12 test
The traditional method of diagnosing vitamin B12 deficiency has been to measure the concentration of total vitamin B12 in serum. The total vitamin B12 concentration essentially reflects vitamin B12 which is bound to its two carrier proteins, forming holohaptocorrin (holoHC) and holotranscobalamin (holoTC). Whilst holoHC accounts for 70 % – 80 % of the vitamin […]