DPD identification is key in avoiding serious reaction to 5-FU cancer drug
Before starting cancer treatment with fluoropyrimidine-based chemotherapies, it is highly recommended to check for dihydropyrimidine dehydrogenase (DPD) deficiency by measuring uracilemia (or calculating the dihydrouracil:uracil ratio). This article discusses some of the ways of doing this. Background Approved for treatment of humans 60 years ago, fluoropyrimidinebased chemotherapies remain important antineoplastic agents. They are widely used […]
