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Genetic variants tied to increased risk of bone complications in young leukaemia patients

Variations in genes involved in normal bone development are associated with an 8- to 15-fold increased risk for osteonecrosis in young patients with acute lymphoblastic leukaemia (ALL), according to research led by St. Jude Children’s Research Hospital and Children’s Oncology Group investigators. Osteonecrosis is a major side effect of ALL treatment with chemotherapy. About 15 […]