Human PCSK9 ELISA
PCSK9 protein (proprotein convertase subtilisin/kexin type 9) plays a major regulatory role in cholesterol homeostasis, mainly by reducing LDL-Receptor levels on the surface of hepatic cells. Reduced LDLR levels result in decreased metabolism of LDL-particles, which could lead to hypercholesterolemia. This activity made PCSK9 a novel target in cholesterol lowering therapy. The PCSK9 inhibitors (PSK9i) […]
