Mutations in notch gene to role in B cell cancers
Notch is one of the most frequently mutated genes in chronic lymphocytic leukaemia (CLL), the most common leukaemia in adults in the United States. It is also often mutated in other common B cell tumours, such as mantle cell lymphoma. However, the role of Notch in these cancers has been uncertain. Now, a collaborative effort […]
