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Scientists make critical insights into T-cell development

Mutations in the gene encoding the enzyme protein tyrosine phosphatase N2 (PTPN2) have been associated with the development of autoimmune disease including Type 1 diabetes, Crohn’s Disease and rheumatoid arthritis. In important fundamental research, Monash University researchers have identified a crucial part of the enzyme’s role in early T-cell development, and have shown that decreased […]