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3

Antibiotics administered to mothers during childbirth linked to autoimmune diseases in children

Children whose mothers have received antibiotic treatment during childbirth are more likely to develop autoimmune diseases compared to their counterparts, according to a recent registry-based study conducted at the University of Oulu, Finland, involving nearly 46,000 children. The most common autoimmune diseases in children include type 1 diabetes, celiac disease, and rheumatic diseases. However, the […]

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New checkpoint identified to fight solid tumours

A study by a scientific team from the University of Vienna and the MedUni Vienna, published in Cellular & Molecular Immunology [1], has a promising result from tumour research: The enzyme phosphoglycerate dehydrogenase (PHDGH) acts as a metabolic checkpoint in the function of tumour-associated macrophages (TAMs) and thus on tumour growth. Targeting PHGDH to modulate […]

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VUB research team discovers essential protein that contributes to liver fibrosis

Chronic liver disease is a serious global health problem that has a severe impact on personal quality of life. A major characteristic of chronic liver disease is liver fibrosis, where certain liver cells, called hepatic stellate cells, become activated and produce scar tissue that damages the liver. At present, no specific drugs are available to […]

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Scientists develop simple blood test to quickly diagnose sarcoidosis

A research project led by Lobelia Samavati, M.D., professor of internal medicine and molecular medicine and genetics at the Wayne State University School of Medicine, and supported by the National Institutes of Health (NIH), has developed a tool to rapidly and inexpensively diagnose sarcoidosis, a chronic inflammatory disease marked by the growth of tiny lumps […]